1121599-71-0

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 91904-13-1 1-(2,4,6-trimethyl phenyl)piperazine 
• 100239-86-9 1-mesityl-4-tosylpiperazine 

Downstream Products

• 1429754-87-9 tert-butyl 4-mesityl-6-(2-nitro-1-phenylethyl)-3,4-dihydropyrazine-1(2H)-carboxylate 

Relevant academic research and scientific papers

Iron-catalyzed oxidative C(3)-H functionalization of amines

Fe-catalyzed direct dehydrogenative C(3)-functionalization of tertiary arylamines was developed via activation of the sp3 C(3)-H bond. The reaction is applicable to both cyclic and acyclic amines. The key process is the catalytic desaturative enamine formation from tertiary amines and position-selective C-C bond formation (addition to nitro olefins) at the β-carbon. Products can be converted to versatile and unique nitrogen-containing molecules.