1121627-40-4

Basic information

• Product Name: 4-chloro-2-(4-chlorophenylcarbamoyl)phenyl 2-(benzyloxycarbonylamino)acetate
• Synonyms: 4-chloro-2-(4-chlorophenylcarbamoyl)phenyl 2-(benzyloxycarbonylamino)acetate
• CAS NO: 1121627-40-4
• Molecular Weight: 473.312
• Mol File: 1121627-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-2-(4-chlorophenylcarbamoyl)phenyl 2-(benzyloxycarbonylamino)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-(4-chlorophenylcarbamoyl)phenyl 2-(benzyloxycarbonylamino)acetate(1121627-40-4)
• EPA Substance Registry System: 4-chloro-2-(4-chlorophenylcarbamoyl)phenyl 2-(benzyloxycarbonylamino)acetate(1121627-40-4)

Safety Data

• Hazardous Substances Data: 1121627-40-4(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 1147-98-4 4',5-dichlorosalicylanilide 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 321-14-2 5-chloro-2-hydroxybenzoic acid 

Relevant articles and documents

Salicylanilide esters of N-protected amino acids as novel antimicrobial agents

A series of novel, highly antimicrobial salicylanilide esters of N-protected amino acids were synthesized and characterized. Their in vitro antimicrobial activity against eight fungal strains and Mycobacterium tuberculosis was determined. The compounds had the highest level of activity against Aspergillus fumigatus, Absidia corymbifera and Trichophyton mentagrophytes, and these levels were higher than that of the standard drug fluconazole. In addition, three compounds showed interesting antituberculosis activity, with inhibition ranging from 89% to 99%. (S)-4-Chloro-2-(4-trifluoromethylphenylcarbamoyl)-phenyl 2-benzyloxy-carbonylamino-propionate had the highest level of both antifungal and antimycobacterial activity. The structure-activity relationships of the new compounds are discussed.