1121703-21-6

Basic information

• Product Name: C₃₁H₃₆N₂O₈
• Synonyms: C₃₁H₃₆N₂O₈
• CAS NO: 1121703-21-6
• Molecular Weight: 564.635
• Mol File: 1121703-21-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₃₆N₂O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₃₆N₂O₈(1121703-21-6)
• EPA Substance Registry System: C₃₁H₃₆N₂O₈(1121703-21-6)

Safety Data

• Hazardous Substances Data: 1121703-21-6(Hazardous Substances Data)

Upstream product

• 1121703-08-9 C₁₉H₂₄N₂O₄ 
• 1084-74-8 3-(2,5-dimethoxybenzoyl)propionic acid 

Downstream Products

• 1121703-39-6 C₃₁H₃₄N₂O₈ 

Relevant articles and documents

Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors

The involvement of μ-calpain in neurological disorders, such as stroke and Alzheimer's disease has attracted considerable interest in the use of calpain inhibitors as therapeutic agents. 4-Aryl-4-oxobutanoic acid amide derivatives 4 were designed as acyclic variants of μ-calpain inhibitory chromone and quinolinone derivatives. Of the compounds synthesized, 4c-2, which possesses a 2-methoxymethoxy group at the phenyl ring and a primary amide at the warhead region most potently inhibited μ-calpain (IC50 = 0.34 μM). Our findings suggest that the 4-aryl-4-oxobutanoic acid amide derivatives should be considered as a new family of μ-calpain inhibitors.