1122091-19-3

Upstream product

• 1122090-99-6 2-acetoxy-3-(4-methoxybenzyloxy)propyl tosylate 
• 109786-77-8 (S)-3-((4-methoxybenzyl)oxy)propane-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 
• 128461-65-4 3-(p-methoxybenzyloxy)propanal 
• 1350928-33-4 (S)-3-(4-methoxybenzyloxy)-2-(phenylaminooxy)propan-1-ol 

Downstream Products

• 1355509-79-3 (S)-tert-butyl((1-((4-methoxybenzyl)oxy)but-3-en-2-yl)oxy)dimethylsilane 
• 1350928-34-5 (S)-tert-butyl(1-(4-methoxybenzyloxy)but-3-en-2-yloxy)diphenylsilane 
• 1353990-64-3 C₂₇H₃₂O₄Si 
• 1350928-35-6 (S,Z)-tert-butyl(1-(4-methoxybenzyloxy)undec-3-en-2-yloxy)diphenylsilane 
• 1350928-39-0 (S,E)-1-(4-methoxybenzyloxy)undec-3-en-2-ol 
• 80910-01-6 (S)-2-[(4-methoxybenzyloxy)methyl]oxirane 

Relevant academic research and scientific papers

A flexible organocatalytic enantioselective synthesis of heptadeca-1-ene-4,6-diyne-3S,8R,9S,10S-tetrol and its congeners

A unified enantioselective route is developed for the synthesis of heptadeca-1-ene-4,6-diyne-3S,8R,9S,10S-tetrol and its synthetic congeners. A proline-catalyzed aminoxylation, cross-metathesis, Wittig reaction, and catalytic dihydroxylation are key steps

Deracemization of 1,2-diol monotosylate derivatives by a combination of enzymatic hydrolysis with the Mitsunobu inversion using polymer-bound triphenylphosphine

The deracemization of 1,2-diol monotosylate derivatives is achieved by the sequential combination of enzymatic hydrolysis and Mitsunobu inversion using a polymer-bound triphenylphosphine. After the lipase-catalysed hydrolysis of the racemic 2-acetoxyhexyl tosylate, the subsequent Mitsunobu reaction without separation causes an inversion of the resulting (R)-alcohol to give the (S)-enantiomer of the acetate as a single product. In particular, the reaction using the polymer-bound triphenylphosphine also proceeds smoothly, and the product is easily separated by filtration from the polymer-bound reagent and its by-products. This deracemization process is applicable to the preparation of several optically active 1,2-diol monotosylates.

Preparation of optically active 1-O-alkyl-3-O-arylsulfonyl-sn-grycerol derivatives: Substrate engineering in enzyme-mediated enantioselective hydrolysis

Lipase PS catalyzes the enantioselective hydrolysis of various 2-acetyl compounds of the 1-O-alkyl-3-O-arylsulfonyl-sn-glycerol derivatives to afford the corresponding optically active compounds. Changing the structure of the 1-O-alkyl and 3-O-arylsulfonyl groups affects both the reactivity and enantioselectivity. Finally, the E value of the reaction for 2-acetyl-3-O-3,5-dimethylbenzenesulfonyl-1-O-4-methoxybenzyl-sn-glycerol is greater than 200. Georg Thieme Verlag Stuttgart.