112211-62-8Relevant academic research and scientific papers
Microwave-assisted dealkoxycarbonylation of α-mono- and α,α-disubstituted β-keto- and α-cyanoesters mediated by a silica gel bed
Guerrero-Caicedo, Alejandro,Soto-Martínez, Diana M.,Abonia, Rodrigo,Jaramillo-Gómez, Luz M.
, p. 2649 - 2657 (2018)
A new alternative protocol for the classical Krapcho reaction is reported herein, involving a microwave-assisted method, which replaces the typical aprotic polar solvent with a silica gel support along with the addition of only a few μL of DMF to enhance
Synthesis of Polysubstituted 2-Naphthols by Palladium-Catalyzed Intramolecular Arylation/Aromatization Cascade
Cai, Jinhui,Hu, Xu-Dong,Liu, Wen-Bo,Wang, Zhen-Kai,Yao, Fei,Zhang, Yun-Hao
supporting information, (2020/02/25)
A palladium-catalyzed intramolecular α-arylation and defluorinative aromatization strategy for the synthesis of polysubstituted 2-naphthols is reported. With ortho-bromobenzyl-substituted α-fluoroketones as the substrates and palladium acetate/triphenylphosphine as the catalyst, this method features good functional group tolerance, readily available catalyst and starting materials, and high yields. The applications of the strategy are demonstrated by the synthesis of useful building blocks, such as naphtha[2,3-b]furan, naphthol AS-D, and ligands/catalysts. (Figure presented.).
Cyano or Acyl Group Migration by Consecutive Homolytic Addition and β-Fission
Beckwith, Athelstan L. J.,O'Shea, Dennis M.,Gerba, Sendaba,Westwood, Steven W.
, p. 666 - 667 (2007/10/02)
Suitably constituted aryl and alkyl radicals readily rearrange by 1,2- or 1,4-acyl or cyano migration.
