112228-20-3Relevant articles and documents
Diastereoselective Synthesis of the Hydroxyethylene Dipeptide Isostere of Leu-Val
Nishi, Takahide,Kataoka, Mitsuru,Morisawa, Yasuhiro
, p. 1993 - 1996 (2007/10/02)
The synthesis of hydroxyethylene dipeptide isostere of Leu-Val, a transition-state mimic, is described.The key steps of this synthetic approach are the homogeneous asymmetric hydrogenation of γ-keto esters by BINAP-Ru(II) complex, and the construction of