Welcome to LookChem.com Sign In|Join Free
  • or
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene, also known as SMPT, is a heterobifunctional sulfhydryland amine-reactive cross-linker. It is characterized by the presence of a cleavable disulfide bond, a benzene ring, and a methyl group adjacent to a carbon that hinders the disulfide bond, providing exceptional conjugate stability in vivo. SMPT is more stable to hydrolysis in aqueous solutions than other NHS cross-linkers.

112241-19-7

Post Buying Request

112241-19-7 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

112241-19-7 Usage

Uses

Used in Pharmaceutical Industry:
SMPT is used as a cross-linker for conjugating toxin molecules to monoclonal antibodies directed against cell-surface antigens. The resulting immunotoxins are highly potent due to the cleavable disulfide bond, which imparts increased cytotoxicity compared to conjugates without a cleavable bond, such as those produced with SPDP.
Used in Research Applications:
SMPT is employed as a research tool for the development of novel drug delivery systems and the study of protein-protein interactions, as well as for the synthesis of bioconjugates with improved stability and functionality.

Check Digit Verification of cas no

The CAS Registry Mumber 112241-19-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,2,4 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 112241-19:
(8*1)+(7*1)+(6*2)+(5*2)+(4*4)+(3*1)+(2*1)+(1*9)=67
67 % 10 = 7
So 112241-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H16N2O4S2/c1-12(25-26-15-4-2-3-11-19-15)13-5-7-14(8-6-13)18(23)24-20-16(21)9-10-17(20)22/h2-8,11-12H,9-10H2,1H3

112241-19-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,5-dioxopyrrolidin-1-yl) 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate

1.2 Other means of identification

Product number -
Other names 1-({4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoyl}oxy)pyrrolidine-2,5-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112241-19-7 SDS

112241-19-7Upstream product

112241-19-7Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 112241-19-7