1122474-75-2Relevant academic research and scientific papers
β-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: Part 2. Optimization of α-amino substituents
Yang, Shyh-Ming,Scannevin, Robert H.,Wang, Bingbing,Burke, Sharon L.,Huang, Zhihong,Karnachi, Prabha,Wilson, Lawrence J.,Rhodes, Kenneth J.,Lagu, Bharat,Murray, William V.
, p. 1140 - 1145 (2008/09/19)
The introduction and the optimization of an α-amino substituent based on a series of α-hydroxy-β-N-biaryl ether sulfonamide hydroxamates is described. The modification leads to a new series of MMP-2/MMP-9 inhibitors with enhanced inhibitory activities and
