1122498-65-0Relevant academic research and scientific papers
Aza-annulation of β-enaminolactones: application to the synthesis of enantiopure difunctionalized bicyclic lactams
Alladoum, Jeanne,Toum, Valérie,Hebbe, Séverine,Kadouri-Puchot, Catherine,Dechoux, Luc
, p. 617 - 619 (2009)
Diastereoselective aza-annulation of seven-membered β-enaminolactones 2 gives access to bicyclic heterocyles 5. Fragmentation of molecule 5a with lithium methoxide affords cis or trans bicyclic lactams 8 with excellent stereoselectivities.
