112251-86-2

Usage

Uses

Used in Pharmaceutical Industry:
2,5-Cyclohexadien-1-one, 4-methyl-3,4-dinitrois used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its ability to be transformed into different aromatic structures makes it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 2,5-Cyclohexadien-1-one, 4-methyl-3,4-dinitrois utilized as an intermediate in the production of pesticides and other agrochemicals, contributing to the development of effective solutions for crop protection and management.
Used in Organic Synthesis:
2,5-Cyclohexadien-1-one, 4-methyl-3,4-dinitrois employed as a key component in the preparation of a range of aromatic compounds. Its versatility in organic synthesis allows for the creation of diverse chemical entities for various applications across different industries.

Upstream product

• 17484-36-5 4-Methyl-3-nitroanisole 
• 108-24-7 acetic anhydride 
• 2042-14-0 4-methyl-5-nitrophenol 

Relevant academic research and scientific papers

ipso NITRATION. XXIX. NITRATION OF SUBSTITUTED 4-METHYLANISOLES AND PHENOLS

Nitration of 2-chloro-4-methylanisole (1a) in acetic anhydride gives (Z)-4-chloro-3-methoxy-6-methyl-6-nitrocyclohexa-2,4-dienyl acetate (2a), 2-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone (3a), and 2-chloro-4-methyl-6-nitroanisole (4a).Similarly 2-bromo-4-methylanisole (1b) gives (Z)-4-bromo-3-methoxy-6-methyl-6-nitrocyclohexa-2,4-dienyl acetate (2b), 2-bromo-4-methyl-4-nitrocyclohexa-2,5-dienone (3b), and 2-bromo-4-methyl-6-nitroanisole (4b), whereas 4-methyl-2-nitro-anisole (1c) gives (Z)-3-methoxy-6-methyl-4,6-dinitrocyclohexa-2,4-dienyl acetate (2c), (Z)-3-methoxy-6-methyl-2,6-dinitrocyclohexa-2,4-dienyl acetate (7), and 4-methyl-2,6-dinitroanisole (4c).Nitration of 3-chloro-4-methylanisole (9a) gives 3-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone (10a), 3-chloro-4-methyl-2-nitro anisole (11a), and 5-chloro-4-methyl-2-nitroanisole (12a), and 4-methyl-3-nitroanisole (9c) gives (Z)-3-methoxy-6-methyl-5,6-dinitrocyclohexa-2,4-dienyl acetate (13), 4-methyl-2,3-dinitroanisole (11c), and 4-methyl-2,5-dinitroanisole (12c).Nitration of 2-chloro-4-methylphenol (14) in chloroform gives 3a and 2-chloro-4-methyl-6-nitrophenol (5a), and 3-chloro-4-methylphenol (15) gives dienone 10a, 3-chloro-4-methyl-2-nitrophenol (16), and 5-chloro-4-methyl-2-nitrophenol (17).