1122570-45-9

Basic information

• Product Name: 2-benzoyl-1-(2-cyano-benzyl)-3-methyl-1,2-dihydroisoquinoline-1-carbonitrile
• Synonyms: 2-benzoyl-1-(2-cyano-benzyl)-3-methyl-1,2-dihydroisoquinoline-1-carbonitrile
• CAS NO: 1122570-45-9
• Molecular Weight: 389.456
• Mol File: 1122570-45-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzoyl-1-(2-cyano-benzyl)-3-methyl-1,2-dihydroisoquinoline-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzoyl-1-(2-cyano-benzyl)-3-methyl-1,2-dihydroisoquinoline-1-carbonitrile(1122570-45-9)
• EPA Substance Registry System: 2-benzoyl-1-(2-cyano-benzyl)-3-methyl-1,2-dihydroisoquinoline-1-carbonitrile(1122570-45-9)

Safety Data

• Hazardous Substances Data: 1122570-45-9(Hazardous Substances Data)

Upstream product

• 21259-77-8 2-benzoyl-3-methyl-1,2-dihydroisoquinoline-1-carbonitrile 
• 22115-41-9 2-(bromomethyl)benzonitrile 

Downstream Products

• 1122570-48-2 2-(3-methylisoquinolin-1-ylmethyl)benzonitrile 

Relevant articles and documents

Synthesis of 6-methyl-8H-dibenzo[a,g]quinolizin-8-imines via Reissert compounds

Alkylation of Reissert compounds derived from 3-methylisoquinolines with several 2-cyanobenzylbromides followed by hydrolytic cleavage provided the corresponding 1-benzyl-3-methylisoquinolines. Treatment of the latter with methylmagnesiumiodide caused cyclization to the title compounds rather than formation of 2-acetylbenzylisoquinolines.