1122589-14-3Relevant academic research and scientific papers
Synthesis and antioxidant properties of some new 3-(4-chlorophenyl)-5- (pyridin-4-yl)-4H-1,2,4-triazole derivatives
Bekircan, Olcay,?zen, Tevfik,Gümrükcüo?lu, Nurhan,Bekta?, Hakan
, p. 548 - 554 (2008)
A series of new 3-(4-chlorophenyl)-5-(pyridin-4-yl)-4-(arylmethyleneamino)- 4H-1,2,4-triazole derivatives 3 were prepared in good yields by treatment of 4-amino-3-(4-chlorophenyl)-5-(pyridine-4-yl)-4H-1,2,4-triazole (2) with selected aldehydes. Compounds 3 were reduced with NaBH4 to afford the corresponding 3-(4-chlorophenyl)-5-(pyridin-4-yl)-4-(arylmethylamino)-4H-1,2,4- triazole derivatives 4. Eighteen new compounds were synthesized and characterized by elemental analyses, IR, 1H NMR and 13C NMR spectral data. The compounds were screened for their antioxidant and antiradical activities.
