112260-57-8

Upstream product

• 19488-48-3 methyl 2,3,6-tri-O-benzyl-α-D-galactopyranoside 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 29600-81-5 methyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-galactopyranoside 

Downstream Products

• 127214-50-0 methyl 2,3,6-tri-O-benzyl-4-cyano-4-deoxy-α-D-glucopyranoside 
• 71454-41-6 methyl 2,3,6-tri-O-benzyl-4-deoxy-4-fluoro-α-D-glucopyranoside 
• 68622-25-3 Methyl 4-azido-2,3,6-tri-O-benzyl-4-deoxy-α-D-glucopyranoside 
• 172297-88-0 methyl 2,3,6-tri-O-benzyl-4-deoxy-β-L-threo-hex-4-enopyranoside 
• 214784-08-4 methyl 2,3,6-tri-O-benzyl-4-O-phthalimido-α-D-glucopyranoside 
• 1401709-32-7 2,3,6-tri-O-benzyl-4-deoxy-4-fluoro-D-galactopyranose 
• 1401709-33-8 2,3,6-tri-O-benzyl-4-deoxy-4-fluoro-D-galactopyranose 
• 1401709-34-9 1-O-acetyl-2,3,6-tri-O-benzyl-4-deoxy-4-fluoro-D-galactopyranose 
• 1401709-35-0 1-O-acetyl-2,3,6-tri-O-benzyl-4-deoxy-4-fluoro-D-galactopyranose 
• 1401709-28-1 methyl 2,3,6-tri-O-benzyl-4-deoxy-4-fluoro-α-D-galactopyranoside 
• 152581-83-4 [1-Benzyl-piperidin-(2E)-ylidene]-((2S,3R,4S,5R,6S)-4,5-bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yl)-amine 
• 4097-98-7 methyl 2,3,6-tri-O-benzyl-4-amino-4-deoxy-α-D-glucopyranoside 
• 214784-09-5 methyl 4-O-amino-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 130515-47-8 methyl 4-S-acetyl-2,3,6-tri-O-benzyl-4-thio-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of 2-fluoro and 4-fluoro galactopyranosyl phosphonate analogues of UDP-Gal

Two novel nonisosteric UDP-Gal analogues, (2-deoxy-2-fluoro- and 4-deoxy-4-fluoro-α-D-galactopyranosyl) phosphonoyl phosphates, were synthesized by optimized multistep procedures starting from 3,4,6-tri-O-benzyl- D-galactal and allyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside, respectively. The key steps were a Michaelis-Arbuzov reaction of respective deoxy-fluoro-D-galactopyranosyl acetate with triethyl phosphite followed by a Moffatt-Khorana coupling reaction with UMP-morpholidate. The structure of all new compounds was confirmed by NMR and mass spectroscopies.

Synthesis of glucose derivatives modified at the 4-OH as potential chain-terminators of cellulose biosynthesis; Herbicidal activity of simple monosaccharide derivatives

A series of d-glucose derivatives that have been modified at C-4 were synthesised from D-galactose as potential chain terminators of cellulose biosynthesis. Two compounds displayed herbicidal activity in pre-emergence tests and in addition a cell expansio

The first synthesis of secondary sugar sulfonic acids by nucleophilic displacement reactions

The 4-deoxy-4-C-sulfonic acid and 6-deoxy-6-C-sulfonic acid derivatives of methyl α-D-gluco- and α-D-galactopyranosides were prepared by triflate-mediated nucleophilic displacement reactions, either with NaHSO 3 or with AcSK. The triflate ester

Inhibition of Glycosidases by Lactam Oximes: Influence of the Aglycon in Disaccharide Analogues

The influence of a substituent at the hydroximo function of the lactam analogue 1 on the inhibition of β- and α-glucosidases is evaluated. In contrast to 1, the O-alkyl oximes 5, 6, 9, and 10 are selective inhibitors of β-glucosidases. Alkylation of the D

α-glucosidase inhibitors

This invention relates to novel polyglycosidyl derivatives of 1-deoxy-nojirimycin, to the processes for their preparation and to their end-use applications, particularly as to their use in the treatment of diabetes.

Stereospecific carbon-carbon bond formation at secondary carbons in cyclic sugars

An excellent leaving-group, triflate, at C-4 of the benzylated hexopyranose glycosides 1 and 2 was used to study the introduction of carbon branches in sugars. By using a phase-transfer reagent, a one-carbon source, cyanide ion, was used to prepare the di

Amidine pseudodisaccharides

The synthesis of several aminoglucopyranose-based amidine pseudodisaccharides is described. They may serve as glycosidase inhibitors by virtue of structural similarities to both the reducing and non-reducing pyranose units involved in glycolysis.

α-glucosidase inhibitors

This invention relates to novel N-glycosyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol, to the chemical processes for their preparation, to their α-glucosidase inhibiting properties, and to their end-use application in the treatment of diabetes, obe

Novel alpha-glucosidase inhibitors

This invention relates to novel N-derivatives, of 1,4-di--deoxy-1,4-imino-L-arabinitol (I), to the processes for their preparation and to their end-use applications, particularly as to their use in the treatment of diabetes. wherein n is zero, one or two,