112288-98-9

Upstream product

• 4613-15-4 benzyl 4-O-benzyl-α-L-rhamnopyranoside 
• 69558-10-7 benzyl 2-O-allyl-4-O-benzyl-α-L-rhamnopyranoside 
• 89316-01-8 benzyl 2-O-allyl-4-O-benzyl-3-o-methyl-α-L-rhamnopyranoside 

Downstream Products

• 69621-36-9 benzyl 4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside 
• 112288-93-4 benzyl O-(2,3,4-tri-O-acetyl-6-O-methyl-β-D-glucopyranosyl)-(1->4)-O-(2,3-di-O-methyl-α-L-rhamnopyranosyl)-(1->2)-4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside 
• 112288-94-5 benzyl O-(2,3,4-tri-O-acetyl-6-O-methyl-β-D-glucopyranosyl)-(1->4)-O-(2,3-di-O-methyl-β-L-rhamnopyranosyl)-(1->2)-4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside 
• 112288-91-2 benzyl O-(2,3,4,6,-tetra-O-acetyl-β-D-glucopyranosyl)-(1->4)-O-(2,3-di-O-methyl-α-L-rhamnopyranosyl)-(1->2)-4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside 
• 112288-92-3 benzyl O-(2,3,4,6,-tetra-O-acetyl-β-D-glucopyranosyl)-(1->4)-O-(2,3-di-O-methyl-β-L-rhamnopyranosyl)-(1->2)-4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside 

Relevant academic research and scientific papers

CHEMICAL SYNTHESIS OF THE TRISACCHARIDE UNIT OF THE SPECIES-SPECIFIC PHENOLIC GLYCOLIPID FROM mycobacterium leprae

O-(3,6-Di-O-methyl-β-D-glukopyranosyl)-(1->4)-O-(2,3-di-O-methyl-α-L-rhamnopyranosyl)-(1->2)-3-O-methyl-L-rhamnopyranose, the haptenic trisaccharide of the Mycobacterium leprae-specific phenolic glycolipid I (PGL-I) antigen, and related trisaccharides, we

Synthesis of the Neoglycoconjugates of Phenolic Glycolipid-related Trisaccharides for the Serodiagnosis of Leprosy

The trisaccharide segment of the phenolic glycolipid I of Mycobacterium leprae was synthesized effectively in the form of p-(2-methoxycarbonylethyl)phenyl glycoside by the condensation of p-(2-methoxycarbonylethyl)phenyl 4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside and 2,3-di-O-methyl-4-O-(2,4-di-O-acetyl-3,6-di-O-methyl-β-D-glucopyranosyl)-α-L-rhamnopyranosyl chloride in the presence of silver triflate and 1,1,3,3-tetra-N-methylurea, and subsequent selective deprotection.This was then coupled to BSA by the acyl azide method, giving NT-P-BSA.The NT-P-BSA showed very high reactivity and specificity to leprosy sera.The trisaccharide-BSA conjugate with a β-linked rhamnosylrhamnose unit (βT-P-BSA) was also synthesized.