112290-77-4Relevant academic research and scientific papers
Practical bromination of arylhydroxylamines with SOBr2 towards ortho-bromo-anilides
Du, Yuanbo,Feng, Lei,Gao, Hongyin,Guo, Lirong,Lu, Haifeng,Xi, Zhenguo
, (2021)
A facile approach for synthesizing ortho-bromoanilides from readily available aryhydroxylamines and thionyl bromide is demonstrated in this work. Mild reaction conditions and broad scope of substrates ranging from heterocyclic structures to pharmaceutics-potential motifs are used in the reactions of this paper. Efficient bromination of ortho C–H bonds of the aryhydroxylamines has been achieved. Ortho-bromoanilide products were obtained in good to excellent yields, and model scaled-up reactions of this synthetic approach are shown in this work.
SYNTHESE VON GLOSSOBALOL UND BALANOGLOSSOL
Martin, Pierre
, p. 1645 - 1646 (2007/10/02)
An efficient method for the first synthesis of the two natural indoles 3 and 5 (produced by acorn worms, Enteropneusta) is presented.The key step is a hetero-Cope rearrangement of an intermediate N-phenyl-O-vinylhydroxylamine derivative.
