112291-46-0

Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 95-54-5 1,2-diamino-benzene 
• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 3171-45-7 4,5-dimethyl-1,2-phenylenediamine 
• 326012-64-0 4b,9b-dihydroxy-8-methoxy-4bH-benzo[d]indeno[1,2-b]-furan-10(9bH)-one 
• 1616869-71-6 C₁₆H₁₃NO₄ 
• 150-76-5 4-methoxy-phenol 

Relevant academic research and scientific papers

Synthesis of 2-arylbenzimidazoles catalyzed by transition metal nitrates

A simple and practical procedure for synthesis of 2-arylbenzimidazoles by a one-pot condensation of o-phenylenediamine with aromatic aldehydes in the presence of a catalytic amount of M(NO3)2·6H 2O (M = Mn, Fe, Co, Ni, Cu)

Synthesis and fungicidal activity of novel 6H-benzimidazo[1,2-c][1,3]benzoxazin-6-ones

[Figure not available: see fulltext.] A series of 6H-benzimidazo[1,2-c][1,3]benzoxazin-6-one derivatives were synthesized in moderate to good yield by reaction of 2-(1H-benzimidazol-2-yl)phenols with triphosgene, and the structures of the target compounds

The ninhydrin core as carbonyl source to access 2-(2′-hydroxyaryl)benzimidazoles exploiting the ortho selectivity of ninhydrin-phenol adducts

Although ninhydrin is an essential analytical tool in biochemical and forensic sciences, for the past several years, it has been employed as efficient building block for diverse organic scaffolds. In the present work, the ortho selectivity of ninhydrin-phenol adducts has been exploited to obtain 2-(2′-hydroxyaryl)benzimidazoles which are well known excited state intramolecular proton transfer (ESIPT) fluorophores. Under acidic condition, 3-(2-hydroxyaroyl)isoindolin-1-one intermediate generated in situ from ninhydrin-phenol adducts was treated with o-phenylenediamine resulting benzimidazole scaffolds via a two-step one pot strategy.