112296-59-0Relevant academic research and scientific papers
Design and synthesis of a novel series of pyranonaphthoquinones as topoisomerase II catalytic inhibitors
Jiménez-Alonso, Sandra,Orellana, Haydee Chávez,Estévez-Braun, Ana,Ravelo, Angel G.,Pérez-Sacau, Elisa,Machín, Felix
, p. 6761 - 6772 (2008)
On the basis of previous pharmacophore modeling studies of naphthoquinones derivatives, we have designed and synthesized a new set of pyranonaphthoquinones. These compounds were obtained through a direct and highly efficient approach based on an intramole
Enantioselective alkynylation reactions to aldehydes: The effects of aromatic substituents upon the enantioselectivity
Tyrrell, Elizabeth,Tesfa, Kibur Hunie,Millet, Julien,Muller, Christophe
, p. 3099 - 3105 (2008/02/10)
Asymmetric alkynylation reactions to linear alkyl and substituted aromatic aldehydes have been accomplished in good yields and with a range of selectivities. For aromatic aldehydes we observed that the selectivity of the alkynylation reaction appears to d
