1123-40-6

Usage

Uses

Used in Pharmaceutical Industry:
3,3-Dimethylglutarimide is used as a barbital substitute for its ability to mimic the properties of barbital in pharmaceutical formulations. This substitution can lead to improved safety profiles and reduced side effects compared to traditional barbital-based compounds.
Used in Chemical Synthesis:
3,3-Dimethylglutarimide is used as a key intermediate in the synthesis of various organic compounds, particularly in the formation of heterodimers. Its unique chemical structure allows for the creation of novel molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
3,3-Dimethylglutarimide is utilized in research and development settings to explore its potential applications and properties. Its ability to form heterodimers and act as a barbital substitute makes it an interesting compound for scientists to study and develop new applications and products.

Purification Methods

Recrystallise the imide from hot H2O or EtOH [Arnett & Harrelson J Am Chem Soc 109 809 1987]. [Beilstein 21 H 391, 21 I 331, 21 II 309, 21 III/IV 4601, 21/9 V 592.]

InChI:InChI=1/C7H11NO2/c1-7(2)3-5(9)8-6(10)4-7/h3-4H2,1-2H3,(H,8,9,10)

Upstream product

• 4160-82-1 3,3-dimethylglutaric anhydride 
• 77287-34-4 formamide 
• 57-13-6 urea 
• 77406-71-4 2-cyano-3,3-dimethyl-glutaric acid-5-ethyl ester 
• 4839-46-7 3,3-Dimethylglutaric acid 
• 38597-82-9 4,4-dimethyl-6-acetonylpiperid-2-one 
• 6630-38-2 5-cyano-2-imino-4,4-dimethyl-6-oxo-piperidine-3-carboxylic acid amide 
• 871901-54-1 5-cyano-4,4-dimethyl-2,6-dioxo-piperidine-3-carboxylic acid 
• 66393-63-3 N-bromo-3,3-dimethylglutarimide 
• 274690-12-9 2-cyano-3,3-dimethyl-glutaric acid diethyl ester 
• 854704-89-5 4,4-dimethyl-2,6-dioxo-piperidine-3-carbonitrile 

Downstream Products

• 4045-30-1 4,4-dimethylpiperidine 
• 83928-76-1 gepirone 
• 142336-22-9 Mesmar 
• 25115-67-7 N,3,3-trimethylglutarimide 
• 38646-68-3 4,4-dimethylpiperidine hydrochloric acid salt 
• 4839-46-7 3,3-Dimethylglutaric acid 
• 811811-84-4 4-(tert-butyldimethylsilanyloxy)piperidine-1-carboxylic acid 4-[2-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)ethyl]phenyl ester 
• 777859-91-3 1-[2-(2-methoxy-5-nitrophenoxy)ethyl]-4,4-dimethylpiperidine-2,6-dione 
• 148554-41-0 trans-bis(3,3-dimethylglutarimidato)bis(1-phenylethylamine)copper(II) 
• 92059-78-4 4,4-dimethyl-1-phenylpiperidine-2,6-dione 
• 1350473-57-2 (Z)-1-benzyl-3-(hydroxyimino)-4,4-dimethylpiperidine-2,6-dione 

Related news

Vibrational spectra and normal coordinate analysis of 3,3-DIMETHYLGLUTARIMIDE (cas 1123-40-6) and its mercury(II) complex09/24/2019

FT-Raman and FT-IR spectra are reported for 3,3-dimethylglutarimide, its N-deuterated derivative and the Hg(II) complex with 3,3-dimethylglutarimidate ion, Hg(C7H10NO2)2·H2O. A complete vibrational assignments are given for all internal vibrations of the molecules and are supported by normal co...detailed

Relevant academic research and scientific papers

Spin state modulation of iron spin crossover complexes via hydrogen-bonding self-assembly

Iron complexes derived from 6-diaminotriazyl-2,2′-bipyridines display spin crossover behaviour, and hydrogen bonding-controlled self-assembly with a suitable barbiturate partner can modulate the crossover from mixed low and high spin to high spin. This system is the first to use solution-phase self-assembly of complementary hydrogen-bonding organic species to modulate spin state.

Flash Photolysis of N-Bromo-3,3-dimethylglutarimide: Detection of the Imidyl Radical

A transient, ascribed to an imidyl radical, has been observed in the flash photolysis of N-bromo-3,3-dimethylglutarimide in carbon tetrachloride solution; both the transient as well as the precursor were quenched by 3,3-dimethylbut-1-ene while cyclohexane quenched the transient but not the precursor.

AMIDOALKYLPIPERAZINYL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES

The invention relates to novel amidoalkylpiperazinyl derivatives of tricyclic heterocyclic systems of general formula (I), wherein Z represents -NH- and X represents -S-, or Z represents -S- and X represents >C=C1 represents H or -CH3, R6 and R7 both represent H, n is an integer from 0 to 4 inclusive, G represents a cyclic amide or imide moiety, and optical isomers, geometric isomers, and pharmaceutically acceptable salts thereof. The compounds may be useful for the treatment and/or prevention of the central nervous system disorders.

Spin state modulation of iron spin crossover complexes via hydrogen-bonding self-assembly

Iron complexes derived from 6-diaminotriazyl-2,2′-bipyridines display spin crossover behaviour, and hydrogen bonding-controlled self-assembly with a suitable barbiturate partner can modulate the crossover from mixed low and high spin to high spin. This system is the first to use solution-phase self-assembly of complementary hydrogen-bonding organic species to modulate spin state.

SYNTHESIS AND PROPERTIES OF 4,4-DIMETHYLCONIINE DERIVATIVES

In the course of transformations of 4,4-dimethyl-6-acetonylpiperid-2-one, a series of 4,4-dimethylconiine derivatives exhibiting an influence on the arterial blood-pressure was synthesized.The structure of new compounds was established on the basis of spectral data and chemical reactions leading finally to known 4,4-dimethylpiperid-2,6-dione.