1123-48-4

Basic information

• Product Name: 1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone
• Synonyms: 1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone(SALTDATA: FREE);Ethanone,1-(3,5-dimethyl-1H-pyrazol-4-yl)-
• CAS NO: 1123-48-4
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• Mol File: 1123-48-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 129.5-130 °C
• Boiling Point: 289.3°Cat760mmHg
• Flash Point: 133.2°C
• Appearance: /
• Density: 1.104g/cm³
• Vapor Pressure: 0.00221mmHg at 25°C
• Refractive Index: 1.527
• PKA: 12.32±0.50(Predicted)
• CAS DataBase Reference: 1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone(1123-48-4)
• EPA Substance Registry System: 1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone(1123-48-4)

Safety Data

• Hazardous Substances Data: 1123-48-4(Hazardous Substances Data)

Usage

Uses

1-(3,5-Dimethyl-1H-pyrazol-4-yl)ethanone can be used to treat and prevent ophthalmic diseases.

InChI:InChI=1/C7H10N2O/c1-4-7(6(3)10)5(2)9-8-4/h1-3H3,(H,8,9)

Upstream product

• 815-68-9 3-acetylpentane-2,4-dione 

Relevant articles and documents

Study of the reaction of 2-acyl 1,3-dicarbonyl compounds with hydrazines by 1H NMR spectroscopy

The reaction of 2-acyl 1,3-dicarbonyl compounds with hydrazine and phenylhydrazine was studied by 1H NMR spectroscopy.It was shown that the formation of functionally 4-substituted pyrazoles is promoted if the reaction is conducted in protic solvents at reduced temperature.The presence of the benzoyl groups in the 2-acyl 1,3-dicarbonyl compounds leads to the preferential formation of the cleavage products, i.e., the corresponding acylhydrazines and 1,3-dicarbonyl compounds.It was established that the initial reaction product is consumed in two directions, i.e., cyclization with the formation of functionally 4-substituted pyyrazoles and cleavage with the formation of acetylhydrazines and the corresponding 1,3-dicarbonyl compounds.