1123-48-4

Usage

Uses

Used in Ophthalmic Applications:
1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone is used as a therapeutic agent for the treatment and prevention of ophthalmic diseases. Its application in this field is attributed to its potential to target specific biological pathways and mechanisms involved in the development and progression of various eye conditions, thereby offering a promising avenue for managing these disorders and improving patient outcomes.

InChI:InChI=1/C7H10N2O/c1-4-7(6(3)10)5(2)9-8-4/h1-3H3,(H,8,9)

Upstream product

• 815-68-9 3-acetylpentane-2,4-dione 

Relevant academic research and scientific papers

Reaction of 2-(1-alkoxyethylidene) 1,3-dicarbonyl compounds with nitrogen-containing binucleophiles

The reaction of 2-(1-alkoxyethylidene) 1,3-dicarbonyl compounds with hydrazine, phenylhydrazine, urea, and dimethylhydrazine leads to high yields of the corresponding functionally substituted pyrazoles, pyrimidines, and enehydrazines.

Study of the reaction of 2-acyl 1,3-dicarbonyl compounds with hydrazines by 1H NMR spectroscopy

The reaction of 2-acyl 1,3-dicarbonyl compounds with hydrazine and phenylhydrazine was studied by 1H NMR spectroscopy.It was shown that the formation of functionally 4-substituted pyrazoles is promoted if the reaction is conducted in protic solvents at reduced temperature.The presence of the benzoyl groups in the 2-acyl 1,3-dicarbonyl compounds leads to the preferential formation of the cleavage products, i.e., the corresponding acylhydrazines and 1,3-dicarbonyl compounds.It was established that the initial reaction product is consumed in two directions, i.e., cyclization with the formation of functionally 4-substituted pyyrazoles and cleavage with the formation of acetylhydrazines and the corresponding 1,3-dicarbonyl compounds.