1123178-75-5Relevant academic research and scientific papers
Examination of the biological role of the α(2→6)-linked sialic acid in gangliosides binding to the Myelin-Associated Glycoprotein (MAG)
Schwardt, Oliver,G?thje, Heiko,Vedani, Angelo,Mesch, Stefanie,Gao, Gan-Pan,Spreafico, Morena,Von Orelli, Johannes,Kelm, S?rge,Ernst, Beat
supporting information; experimental part, p. 989 - 1004 (2010/03/01)
The tetrasaccharide 1, a substructure of ganglioside GQ1bα, shows a remarkable affinity for the myelin- associated glycoprotein (MAG) and was therefore selected as starting point for a lead optimization program. In our search for structurally simplified a
