1123306-78-4

Basic information

• Product Name: 1,1-dimethylethyl (2R,4R)-4-({[2,5-bis(methyloxy)phenyl]sulfonyl}amino)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate
• Synonyms: 1,1-dimethylethyl (2R,4R)-4-({[2,5-bis(methyloxy)phenyl]sulfonyl}amino)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate
• CAS NO: 1123306-78-4
• Molecular Weight: 545.613
• Mol File: 1123306-78-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl (2R,4R)-4-({[2,5-bis(methyloxy)phenyl]sulfonyl}amino)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl (2R,4R)-4-({[2,5-bis(methyloxy)phenyl]sulfonyl}amino)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate(1123306-78-4)
• EPA Substance Registry System: 1,1-dimethylethyl (2R,4R)-4-({[2,5-bis(methyloxy)phenyl]sulfonyl}amino)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate(1123306-78-4)

Safety Data

• Hazardous Substances Data: 1123306-78-4(Hazardous Substances Data)

Upstream product

• 1123306-57-9 1,1-dimethylethyl (2R,4R)-4-amino-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate 
• 1483-28-9 2,5-dimethoxybenzene-1-sulfonyl chloride 

Downstream Products

• 1123306-80-8 1,1-dimethylethyl (2R,4R)-4-[{[2,5-bis(methyloxy)phenyl]sulfonyl}(phenylmethyl)amino]-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-pyrrolidinecarboxylate 
• 1123306-84-2 1,1-dimethylethyl (2R,4R)-2-(aminomethyl)-4-({[2,5-bis(methyloxy)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate 

Relevant articles and documents

NOVEL CATHEPSIN C INHIBITORS AND THEIR USE

The invention is directed to compounds according to Formula (I) wherein R1, R2a, R2b, R2c, R3, and n are defined below, and to pharmaceutically-acceptable salts thereof. They are cathepsin C inhibitors and can be used in the treatment of diseases mediated