1123311-76-1

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 444902-74-3 3-acetyl-1,7-diphenyl-[1,2,4]-triazolo[4,3-a]pyrimidine-5(1H)-one 

Downstream Products

• 1123311-85-2 3-[tetrazolo[1,5-a]pyrimidin-7-yl]-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-86-3 3-(pyrazol-3-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-82-9 3-(5-(2-benzimidazolyl)-6-oxo-1,6-dihydropyridin-2-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-88-5 3-(2-aminopyrimidin-4-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-78-3 3-(5-ethoxycarbonyl-6-methyl-pyridin-2-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-79-4 3-(5-ethoxycarbonyl-6-phenyl-pyridin-2-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-81-8 3-(5-ethoxycarbonyl-6-oxo-1,6-dihydropyridin-2-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-84-1 3-([1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-77-2 3-(5-acetyl-6-methyl-pyridin-2-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-80-7 3-(5-cyano-6-oxo-1,6-dihydropyridin-2-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1123311-83-0 3-(2,3-dicyanoimidazo[1,2-a]pyrimidin-7-yl)-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1220197-90-9 1,7-diphenyl-3-[3-ethoxycarbonyl-1-(4-nitrophenyl)pyrazole-4-carbonyl]-[1,2,4]-triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1220197-87-4 1,7-diphenyl-3-[3-ethoxycarbonyl-1-(4-methylphenyl)pyrazole-4-carbonyl]-[1,2,4]-triazolo[4,3-a]pyrimidin-5(1H)-one 
• 1220197-64-7 1,7-diphenyl-3-[3-ethoxycarbonyl-1-phenylpyrazole-4-carbonyl]-[1,2,4]-triazolo[4,3-a]pyrimidin-5(1H)-one 

Relevant academic research and scientific papers

Synthesis and antitumor screening of new 1,7-diphenyl-3-(1,3-disubstituted- 1H-pyrazole-4-carbonyl)-[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones

A new series of 3-(1,3-disubstituted-1H-pyrazole-4-carbonyl)-1,7-diphenyl- [1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones 4 was prepared by reaction of the enaminone 2 with hydrazonoyl halides 3. The preliminary screening for antitumor activity of the synthes

Synthesis and reactions of 3-[3-(dimethylamino)propenoyl]-1,7-diphenyl [1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one

3-Acetyl-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one(1) reacts with N,N-dimethylformamide dimethylacetal (DMFDMA) yielding the enaminone 2. The latter compound reacts with active methylene compounds, hydrazine hydrate, hydroxylamine and some heterocyclic amines to afford trisubstituted pyridine, substituted pyrazole, substituted isoxazole and azolopyrimidines. The antimicrobial activities of the compounds prepared were screened.