1123339-59-2Relevant academic research and scientific papers
Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells
Rosenthal, Andrew S.,Chen, Xiaochun,Liu, Jun O.,West, Diana C.,Hergenrother, Paul J.,Shapiro, Theresa A.,Posner, Gary H.
experimental part, p. 1198 - 1203 (2009/12/24)
A new series of 6 dimeric trioxane sulfones has been prepared from the natural trioxane artemisinin in five or six chemical steps. One of these thermally and hydrolytically stable new chemical entities (4c) completely cured malaria-infected mice via a sin
