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Dalfopristin is a semi-synthetic analogue of ostreogrycin A, belonging to the streptogramin class of antibiotics. It is derived from ostreogrycin A through the addition of diethylaminoethylthiol to the 2-pyrroline group, followed by oxidation to the sulfone. These structural modifications result in a more hydrophobic compound with an ionizable group, which allows for the formation of a salt. Dalfopristin is primarily used in combination with quinupristin, with a ratio of 70:30, to exert a synergistic effect against various bacterial infections.

112362-50-2

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112362-50-2 Usage

Uses

Used in Pharmaceutical Industry:
Dalfopristin is used as an antibiotic agent for treating infections caused by staphylococci and vancomycin-resistant Enterococcus faecium. Its hydrophobic nature and ionizable group contribute to its effectiveness when used in combination with quinupristin, enhancing its activity against antibiotic-resistant strains.
Used in Antimicrobial Applications:
Dalfopristin is employed as a component of a synergistic combination with quinupristin, which is highly effective in combating antibiotic-resistant strains of bacteria. The combination product targets multiple sites within the bacterial ribosome, leading to a more potent inhibition of protein synthesis and ultimately resulting in bacterial cell death. This makes Dalfopristin a valuable asset in the fight against antibiotic resistance.

Check Digit Verification of cas no

The CAS Registry Mumber 112362-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,3,6 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 112362-50:
(8*1)+(7*1)+(6*2)+(5*3)+(4*6)+(3*2)+(2*5)+(1*0)=82
82 % 10 = 2
So 112362-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C34H50N4O9S/c1-7-37(8-2)16-17-48(44,45)28-13-15-38-31(28)34(43)47-32(22(3)4)24(6)11-12-29(41)35-14-9-10-23(5)18-25(39)19-26(40)20-30-36-27(21-46-30)33(38)42/h9-12,18,21-22,24-25,28,31-32,39H,7-8,13-17,19-20H2,1-6H3,(H,35,41)/b10-9-,12-11-,23-18-/t24-,25-,28-,31-,32-/m1/s1

112362-50-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Dalfopristin

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112362-50-2 SDS

112362-50-2Upstream product

112362-50-2Downstream Products

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