1123659-48-2Relevant academic research and scientific papers
Synthesis of C-linked immobilized analogs of aloisine A by 'click' chemistry
Haddoub, Rose,Gueyrard, David,Goekjian, Peter G.
body text, p. 741 - 744 (2009/04/19)
An efficient approach for the immobilization of a series of analogs of aloisine A, an in vitro inhibitor of protein kinases, to polymeric supports via a [3+2] cycloaddition reaction is reported.
Identification of potential cellular targets of aloisine A by affinity chromatography
Corbel, Caroline,Haddoub, Rose,Guiffant, Damien,Lozach, Olivier,Gueyrard, David,Lemoine, Jerome,Ratin, Morgane,Meijer, Laurent,Bach, Stephane,Goekjian, Peter
supporting information; experimental part, p. 5572 - 5582 (2009/12/24)
Affinity chromatography was used to identify potential cellular targets of aloisine A (7-n-butyl-6-(4′-hydroxyphenyl)-5H-pyrrolo[2,3b]pyrazine), a potent inhibitor of cyclin-dependent kinases. This technique is based on the immobilization of the drug on a
