112375-05-0

Basic information

• Product Name: 2-BENZYL-2-AZABICYCLO[2.2.1]HEPT-5-ENE
• Synonyms: 2-BENZYL-2-AZABICYCLO[2.2.1]HEPT-5-ENE;2-AZA-2-BENZYLBICYCLO(2.2.1)HEPT-5-ENE;(1S,4R)-5-Benzyl-5-azabicyclo[2.2.1]hept-2-ene
• CAS NO: 112375-05-0
• Molecular Formula: C₁₃H₁₅N
• Molecular Weight: 185.26
• Mol File: 112375-05-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 274.4°C at 760 mmHg
• Flash Point: 109.5°C
• Appearance: /
• Density: 1.103g/cm³
• Vapor Pressure: 0.00543mmHg at 25°C
• Refractive Index: 1.608
• PKA: 8.77±0.20(Predicted)
• CAS DataBase Reference: 2-BENZYL-2-AZABICYCLO[2.2.1]HEPT-5-ENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL-2-AZABICYCLO[2.2.1]HEPT-5-ENE(112375-05-0)
• EPA Substance Registry System: 2-BENZYL-2-AZABICYCLO[2.2.1]HEPT-5-ENE(112375-05-0)

Safety Data

• Hazardous Substances Data: 112375-05-0(Hazardous Substances Data)

Usage

General Description

2-Benzyl-2-azabicyclo[2.2.1]hept-5-ene is a chemical compound with a bicyclic structure containing a benzyl group and an azabicycloheptene moiety. It is commonly used in organic synthesis and pharmaceutical research as a versatile building block for the preparation of various biologically active compounds. 2-BENZYL-2-AZABICYCLO[2.2.1]HEPT-5-ENE has been found to exhibit potential biological and pharmacological activities, making it of interest for drug discovery and development. Its unique structure and functional groups make it a valuable tool in the creation of new chemical entities with therapeutic properties.

InChI:InChI=1/C13H15N/c1-2-4-11(5-3-1)9-14-10-12-6-7-13(14)8-12/h1-7,12-13H,8-10H2

Upstream product

• 3287-99-8 benzylamine hydrochloride 
• 542-92-7 cyclopenta-1,3-diene 
• 50-00-0 formaldehyd 

Downstream Products

• 661463-34-9 N-benzyl-2-oxa-3-azabicyclo[3.2.1]oct-6-ene 
• 116230-22-9 2-benzyl-2-azabicyclo[2.2.1]heptane 
• 140927-00-0 exo-2-benzyl-2-azabicyclo<2.2.1>heptan-5-ol 
• 46407-10-7 exo-2-benzyl-2-azabicyclo<2.2.1>heptan-6-ol 
• 140927-03-3 2,2-Diphenyl-propionic acid (1R,4S,6R)-2-methyl-2-aza-bicyclo[2.2.1]hept-6-yl ester 

Relevant articles and documents

From cyclopentadiene to isoxazoline-carbocyclic nucleosides: a rapid access to biological molecules through aza-Diels-Alder reactions

A rapid access to carbocyclic nucleosides containing a fused isoxazoline ring is proposed through the Grieco cycloaddition of cyclopentadiene to iminium salts. The prolific elaboration of the isoxazoline cycloadducts allowed preparation of the target amin

Polysulfones of new structural types as perspective antioxidant agents

A series of polysulfones of new structural types on the basis of azanorbornenes, 2,2-diallyl-1,1,3,3-tetraethylguanidiniumchloride and tris(diethylamino)diallylaminophosphonium salts were obtained by free radical polymerization reaction. Their antioxidant

A 1,3-Diaza-Claisen rearrangement that affords guanidines

(Chemical Equation Presented) N-Alkyl-N′-tosylthioureas activated by EDCI react with azanorbonenes at room temperature through a 1,3-diaza-Claisen rearrangement, affording highly substituted, bicyclic guanidines in moderate to good yields.