1123787-67-6Relevant articles and documents
Synthetic method of JAK inhibitor
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Paragraph 0035-0037; 0040, (2020/11/26)
The invention discloses a synthesis method of a JAK inhibitor, which is characterized in that: 4-nitro pyrazole and 3-oxetanone are adopted as initial raw materials; a Chan-Lam coupling reaction is performed on the initial raw material 4-nitro pyrazole an
BICYCLIC JAK INHIBITORS AND USES THEREOF
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Paragraph 000253, (2020/10/20)
Provided herein are compounds of Formulas (I), (II), (III), and (IV) and subformulas thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), (II), (III), or (IV) and methods of using the compounds, e.g., in the treatment of immune disorders, inflammatory disorders, and cancer.
ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF
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Paragraph 00669, (2016/09/26)
The present application is related to compounds represented by Formula I, which are novel positive allosteric modulators of α7 nAChRs. The application also discloses the treatment of disorders that are responsive to enhancement of acetylcholine action on α7 nAChRs in a mammal by administering an effective amount of a compound of Formula I.
