112383-01-4

Basic information

• Product Name: Glycine, N-[N-[N-[[(2-methoxy-1-methyl-2-oxoethyl)amino]carbonyl]glycyl]-L-valyl]- , 2-[(phenylmethoxy)carbonyl]-2-propylhydrazide, (S)-
• CAS NO: 112383-01-4
• Molecular Formula: C25H38N6O8
• Molecular Weight: 550.612
• Mol File: 112383-01-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Glycine, N-[N-[N-[[(2-methoxy-1-methyl-2-oxoethyl)amino]carbonyl]glycyl]-L-valyl]- , 2-[(phenylmethoxy)carbonyl]-2-propylhydrazide, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[N-[N-[[(2-methoxy-1-methyl-2-oxoethyl)amino]carbonyl]glycyl]-L-valyl]- , 2-[(phenylmethoxy)carbonyl]-2-propylhydrazide, (S)-(112383-01-4)
• EPA Substance Registry System: Glycine, N-[N-[N-[[(2-methoxy-1-methyl-2-oxoethyl)amino]carbonyl]glycyl]-L-valyl]- , 2-[(phenylmethoxy)carbonyl]-2-propylhydrazide, (S)-(112383-01-4)

Safety Data

• Hazardous Substances Data: 112383-01-4(Hazardous Substances Data)

Upstream product

• 96847-92-6 N-t-butoxycarbonylglycyl-L-valylglycine 
• 109953-68-6 α-azanorvaline benzyl ester 
• 112382-99-7 N-t-butoxycarbonylglycyl-L-valylglycyl-α-azanorvaline benzyl ester 
• 30293-82-4 (S)-(-)-2 isocyanatopropionic acid methyl ester 
• 112383-27-4 Gly-Val-Gly-Aznva-OCH₂Ph*HCl 

Relevant articles and documents

INHIBITORS OF HUMAN LEUCOCYTE ELASTASE. PEPTIDES INCORPORATING AN &α-AZANORVALINE RESIDUE OR A THIOMETHYLENE LINKAGE IN PLACE OF A PEPTIDE BOND

Peptides containing an α-azanorvaline residue at the C-terminus and N- group at the N-terminus have been made as inhibitors of human leucocyte elastase.A number of analogues with an amide bond replaced by a thiomethylene group have also been prepared.The analogues were tested against leucocyte elastase using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as a substrate and the results were obtained as IC50 values.Both types of analogues inhibited the leucocyte elastase; the most potent of these was N--L-valyl-L-prolyl-α-azanorvaline phenyl ester ( 2 ) ( IC50 0.28 μM, Ki 0.02 μM ).