112389-79-4 Usage
Uses
Used in Organic Synthesis:
2,3-Butadien-1-ol, 4-[(4-methylphenyl)sulfonyl]-, benzoate is used as a reagent in organic synthesis for its ability to participate in various chemical reactions. Its sulfonyl and benzoate groups provide unique reactivity, making it a valuable component in the synthesis of complex organic molecules.
Used as a Nucleophilic Catalyst:
In the field of organic chemistry, 2,3-Butadien-1-ol, 4-[(4-methylphenyl)sulfonyl]-, benzoate is utilized as a nucleophilic catalyst to accelerate chemical reactions. Its presence enhances the formation of carbon-carbon and carbon-heteroatom bonds, improving the efficiency and selectivity of the reactions.
Used in Pharmaceutical Industry:
2,3-Butadien-1-ol, 4-[(4-methylphenyl)sulfonyl]-, benzoate has shown potential as a pharmaceutical intermediate. It is used in the production of various medications and biologically active compounds, contributing to the development of new drugs and therapeutic agents.
Used in the Production of Medications and Biologically Active Compounds:
In the pharmaceutical industry, 2,3-Butadien-1-ol, 4-[(4-methylphenyl)sulfonyl]-, benzoate is employed in the synthesis of a wide range of medications and biologically active compounds. Its unique chemical properties and reactivity make it a valuable component in the development of new drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 112389-79-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,3,8 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 112389-79:
(8*1)+(7*1)+(6*2)+(5*3)+(4*8)+(3*9)+(2*7)+(1*9)=124
124 % 10 = 4
So 112389-79-4 is a valid CAS Registry Number.
112389-79-4Relevant academic research and scientific papers
Preparation of Allenic Sulfones and Allenes from the Selenosulfonation of Acetylenes
Back, Thomas G.,Krishna, M. Vijaya,Muralidharan, K. Raman
, p. 4146 - 4153 (2007/10/02)
β-(Phenylseleno)vinyl sulfones 2 are readily obtained from the free-radical selenosulfonation of acetylenes.Compounds 2 isomerize to allyl sulfones 4 under base-catalyzed conditions in nearly quantitative yield, with high stereoselectivity favoring the Z configuration.Allyl sulfones 4 afford generally high yields of allenic sulfones 1 when subjected to oxidation with m-chloroperbenzoic acid or tert-butyl hydroperoxide, followed by selenoxide syn-elimination.The sulfone-stabilized anion intermediates in the isomerizations of 2 to 4 can be alkylated, deuterated,or silylated in the α-position prior to oxidation, providing allenic sulfones with an additional α-substituent.In some cases, spontaneous elimination of the phenylseleno group occurred, producing the allenic sulfone without the need for an oxidation step.Desulfonylation of allyl sulfones 4f, 4c, and 25 with sodium amalgam afforded vinyl selenides that were converted to allenes in moderate to good yields by oxidation-elimination.The copper catalyzed coupling of allyl sulfones 4 with Grignard reagents comprises an alternative route to vinyl selenide precursors of allenes.These procedures permit the synthesis of various α- and γ-substituted allenic sulfones and allenes from acetylenes.
A GENERAL SYNTHESIS OF ALLENIC SULFONES FROM ACETYLENES USING SELENOSULFONATION
Back, Thomas G.,Krishna, M. Vijaya,Muralidharan, K. Raman
, p. 1737 - 1740 (2007/10/02)
Terminal acetylenes were converted to 1- and 3-substituted allenic sulfones via selenosulfonation, deprotonation, alkylation and selenoxide elimination.
