4(1H)-Pyrimidinone, 6-(dimethylamino)(9CI), also known as Lumacaftor, is a chemical compound belonging to the pyrimidine class of organic compounds with the molecular formula C7H9N3O. It is commonly used in pharmaceuticals for its potential therapeutic applications.
Used in Pharmaceutical Industry:
4(1H)-Pyrimidinone, 6-(dimethylamino)(9CI) is used as a therapeutic agent for the treatment of cystic fibrosis, a genetic disorder affecting the lungs and digestive system. It functions by enhancing the activity of the CFTR protein, which is crucial for regulating the transport of salt and water across cell membranes.
Used in Cystic Fibrosis Treatment:
Lumacaftor is employed as a component of combination therapy for managing the symptoms of cystic fibrosis. It has demonstrated efficacy in clinical trials, showing promise as a potential treatment that can improve the quality of life for patients suffering from this condition.

1124-21-6

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Basic information
1. Product Name: 4(1H)-Pyrimidinone, 6-(dimethylamino)- (9CI)
2. Synonyms: 4(1H)-Pyrimidinone, 6-(dimethylamino)- (9CI)
3. CAS NO:1124-21-6
4. Molecular Formula: C6H9N3O
5. Molecular Weight: 139.15516
6. EINECS: N/A
7. Product Categories: PYRIMIDINE
8. Mol File: 1124-21-6.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: 4(1H)-Pyrimidinone, 6-(dimethylamino)- (9CI)(CAS DataBase Reference)
10. NIST Chemistry Reference: 4(1H)-Pyrimidinone, 6-(dimethylamino)- (9CI)(1124-21-6)
11. EPA Substance Registry System: 4(1H)-Pyrimidinone, 6-(dimethylamino)- (9CI)(1124-21-6)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 1124-21-6(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1124-21-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1124-21:
(6*1)+(5*1)+(4*2)+(3*4)+(2*2)+(1*1)=36
36 % 10 = 6
So 1124-21-6 is a valid CAS Registry Number.

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