1124-69-2 Usage
Molecular structure
A tetrahydropyridine ring with four methyl groups attached at the 2,2,6,6 positions
Use in research
Induces Parkinson's disease-like symptoms in animal models for studying the disease
Mechanism of action
Targets the dopaminergic system in the brain, leading to the degeneration of dopaminergic neurons and the onset of Parkinsonian motor deficits
Motor impairments caused by TMT exposure
Tremors, rigidity, and bradykinesia
Value in Parkinson's disease research
Provides a valuable tool for understanding the underlying mechanisms of the disease and testing potential therapeutic interventions
Check Digit Verification of cas no
The CAS Registry Mumber 1124-69-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1124-69:
(6*1)+(5*1)+(4*2)+(3*4)+(2*6)+(1*9)=52
52 % 10 = 2
So 1124-69-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H17N/c1-8(2)6-5-7-9(3,4)10-8/h5-6,10H,7H2,1-4H3
1124-69-2Relevant articles and documents
Synthesis of 2,2,6,6-tetramethylpiperidine derivatives
Kashparova,Kagan,Kashparov,Zhukova
, p. 667 - 668 (2007/10/03)
Diazotization of 4-amino-2,2,6,6-tetramethylpiperidine in acetic or sulfuric acid affords 2,2,6,6-tetramethyl-1,2,3,6-tetrahydropyridine in high yield. Under the same conditions, the corresponding nitroxyl radical transforms into 4-hydroxy-2,2,6,6-tetrame
A Reaction of Nitroxides with Ethyl Mercaptane: A Mild Method for the Conversion of Nitroxides into Their Corresponding Amines
Zakrzewski, Jerzy
, p. 803 - 808 (2007/10/02)
The mild reduction of the nitroxides 1a-j to the corresponding sterically hindered amines 2a-j by means of ethyl mercaptane is reported.The reaction mixtures of 1a,b,g were analyzed by glc/ms.