112404-27-0

Upstream product

• 126-81-8 dimedone 
• 99-73-0 para-bromophenacyl bromide 

Downstream Products

• 112404-33-8 2-Benzyl-2-[2-(4-bromo-phenyl)-2-oxo-ethyl]-5,5-dimethyl-cyclohexane-1,3-dione 
• 713139-91-4 2-(4-bromophenyl)-1-(2-hydroxyethyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one 
• 116458-82-3 1-Benzyl-3-(4-bromo-phenyl)-7,7-dimethyl-7,8-dihydro-6H-indolizin-5-one 
• 116458-76-5 2-(4-Bromo-phenyl)-7a-hydroxy-3a,6,6-trimethyl-3,3a,5,6,7,7a-hexahydro-indol-4-one 
• 116458-79-8 3-(4-Bromo-phenyl)-1,7,7-trimethyl-7,8-dihydro-6H-indolizin-5-one 
• 713139-96-9 2-(4-bromophenyl)-1-(2-iodoethyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one 
• 112404-30-5 2-[2-(4-Bromo-phenyl)-2-oxo-ethyl]-2,5,5-trimethyl-cyclohexane-1,3-dione 

Relevant academic research and scientific papers

Synthesis and cytotoxic activity of new azepino[3′,4′:4,5]pyrrolo[2,1-a]isoquinolin-12-ones

A series of azepino[3′,4′:4,5]pyrrolo[2,1-a]isoquinolin-12-ones (3a-f), that were conformationally restricted analogs of lead compound 2, were designed as potential cytotoxic compounds and synthesized using a radical oxidative aromatic substitution reacti

2-Aryl-7,7-dimethyl-5,6,7,8-tetrahydrothieno[3,2-c]azepin-4-ones from 5,5-dimethyl-1,3-cyclohexanedione

A novel synthesis of substituted thieno[3,2-c]azepinones is described. This new approach uses 5,5-dimethyl-1,3-cyclohexanedione (dimedone) as the starting material. Oxime intermediates are obtained in three steps from the aforementioned diketone. Using th

THE SYNTHESIS AND CHEMISTRY OF AZOLENINES. PART 8. THE PAAL-KNORR REACTION WITH CYCLIC 2-(ACYLMETHYL)-2-ALKYL-1,3-DIKETONES: ISOLATION OF 1-ACYL-1H-PYRROLES VIA REARRANGEMENT

Treatment of cyclic 2-acylmethyl-2-alkyl-1,3-diketones with ammonium acetate under reflux in acetic acid gives moderate to high yields of 1-acyl-1H-pyrroles by rearrangement.Some of the cyclic diketones react quantitatively with liquid ammonia to yield 2-