1124227-47-9Relevant academic research and scientific papers
Efficient, regioselective palladium-catalyzed tandem heck-lsomerization reaction of aryl bromides and non-allylic benzyl alcohols
Crawley, Matthew L.,Phipps, Kristin M.,Goljer, Lgor,Mehlmann, John F.,Lundquist, Joseph T.,Ullrich, John W.,Yang, Cuijian,Mahaney, Paige E.
supporting information; experimental part, p. 1183 - 1185 (2009/08/07)
An efficient and mild method to couple aryl bromides and activated non-allylic alcohols in a Heck reaction with tandem isomerization to selectively afford high yields of 1,5-diarylalkan-1-ones has been developed. Mechanistic insight was gained through NMR studies of products derived from deuterium-labeled intermediates.
