112434-58-9Relevant academic research and scientific papers
Convenient synthesis of linear 2H,6H-pyrano[3,2-g] chromenes from natural occurring compound; visnagin
Abdel-Aziem, Anhar,El-Sawy, Eslam R.,Kirsch, Gilbert
, p. 3419 - 3425 (2019)
A simple and convenient rout for the synthesis of linear 2-imino-2H,6H-pyrano[3,2-g] chromene-6-ones and 2H,6H-pyrano[3,2-g]chromene-2,6-diones has been described starting from natural occurring furochromone; visnagin (1). Ring opening of 1 yielded 6-form
Synthesis of Benzodipyran Derivatives
Gohar, A.-K. M. N.,Abdel-Latif, F. F.,El-Ktatny, M. S.
, p. 274 - 276 (2007/10/02)
The naturally occuring furochromone, visnagin, on oxidation with chromic acid yields 6-formyl-7-hydroxy-5-methoxy-2-methylbenzopyran-4-one (1) which reacts with 2-amino-1,1,3-tricyanoprop-1-ene to give the corresponding 3-substituted benzodipyran derivative (3).The latter reacts with hydrazine hydrate and phenylhydrazine to give the 4-substituted-aminomethylenepyrazole derivatives 4a and 5a respectively.Compound 1 also reacts with 2-amino-3-carboxyl-1,1-dicyanoprop-1-ene, benzoylacetonitrile, thiocyanoacetamide and cyanoacetic acid hydrazide to give the corresponding dipyran derivatives (6, 7a, 8a and 10a).The imino derivatives 3, 4a, 5a, 7a, 8a and 10a can be hydrolysed to the corresponding keto derivatives (6, 4b, 5b, 7b, 8b and 10b).The biological activity of the synthesised compounds is also reported.
