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S-99 is a chemical compound that acts as a potent inhibitor of the enzyme dihydroorotate dehydrogenase (DHODH), which plays a crucial role in the de novo pyrimidine biosynthesis pathway. S-99 has demonstrated antiproliferative effects in various cancer cell lines and possesses anti-inflammatory properties, positioning it as a promising candidate for the development of anticancer and anti-inflammatory drugs. Its specificity in targeting DHODH, a key enzyme in cell proliferation and immune response, highlights S-99's potential for further research and development in oncology and immunology.

1124381-69-6

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1124381-69-6 Usage

Uses

Used in Oncology:
S-99 is used as an anticancer agent for its ability to inhibit the proliferation of various cancer cell lines. It targets the DHODH enzyme, thereby disrupting the de novo pyrimidine biosynthesis pathway essential for cancer cell growth and division.
Used in Inflammatory Disease Treatment:
S-99 is used as an anti-inflammatory agent due to its capacity to modulate immune responses and reduce inflammation. By inhibiting DHODH, it can potentially alleviate symptoms and progression in inflammatory diseases.
Used in Drug Development:
S-99 is utilized as a lead compound in the development of new pharmaceuticals targeting cancer and inflammatory conditions. Its specificity for DHODH makes it a valuable asset in creating targeted therapies with fewer side effects compared to broad-spectrum treatments.
Used in Research:
S-99 serves as a valuable tool in biological and medical research for studying the role of DHODH in cell proliferation and immune response. It aids in understanding the mechanisms of action and potential therapeutic applications in oncology and immunology.

Check Digit Verification of cas no

The CAS Registry Mumber 1124381-69-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,4,3,8 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1124381-69:
(9*1)+(8*1)+(7*2)+(6*4)+(5*3)+(4*8)+(3*1)+(2*6)+(1*9)=126
126 % 10 = 6
So 1124381-69-6 is a valid CAS Registry Number.

1124381-69-6Upstream product

1124381-69-6Downstream Products

1124381-69-6Relevant academic research and scientific papers

TRIAZOLOPYRIDINE COMPOUNDS AND THEIR USE AS ASK INHIBITORS

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Page/Page column 112-113, (2009/04/25)

The present invention relates to triazolopyridine compounds according to Formula (I), their use as medicament, for treating autoimmune disorders, inflammatorydiseases, cardiovascular disceases and/or neurodegenerative diseases and a process for their preparation.

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