112439-08-4

Upstream product

• 43121-23-9 1-(2,4-dichloro-phenoxy)-3,3-dimethyl-1-[1,2,4]triazol-1-yl-butan-2-one 
• 55476-94-3 1-(2,4-Dichloro-phenoxy)-3,3-dimethyl-1-[1,2,4]triazol-1-yl-butan-2-ol 
• 112439-44-8 Toluene-4-sulfonic acid 1-[(2,5-dichloro-phenoxy)-[1,2,4]triazol-1-yl-methyl]-2,2-dimethyl-propyl ester 

Relevant academic research and scientific papers

A Facile Synthesis of Ketene O,N-Acetals and Ketene O,O-Acetals by Tosylate Elimination

Reaction of the alcohols 4 and 5 with p-toluensulfonyl chloride leads to the sulfonic esters 6 and 7, respectively, which on treatment with potassium tert-butylate easily react to give the ketene O,N-acetals 8 and O,O-acetals 9, respectively.The (E/Z) isomers 8 arising from the elimination reaction of 7 were identified by their 1H-NMR data after X-ray analysis of one of the isomers of 8e.On one example it is shown that the elimination reaction proceeds stereoselectively "anti".