112447-71-9 Usage
Molecular weight
370.6
Structure
1H-Indole-4-carboxylic acid, 1-[tris(1-methylethyl)silyl]-, ethyl ester consists of an indole ring with a carboxylic acid group at the 4-position, an ethyl ester group, and three trimethylsilyl groups attached to the 1-position of the indole ring.
Physical properties
The compound is a pale yellow solid with a melting point of 85-88°C.
Solubility
It is soluble in common organic solvents such as dichloromethane, ethyl acetate, and acetonitrile.
Reactivity
1H-Indole-4-carboxylic acid, 1-[tris(1-methylethyl)silyl]-, ethyl ester is known for its ability to protect sensitive functional groups during chemical reactions. The trimethylsilyl groups can be removed under certain conditions to reveal the free carboxylic acid group.
Synthesis
The compound can be synthesized through the reaction of 1H-indole-4-carboxylic acid with trimethylsilyl chloride and ethyl chloroformate in the presence of a base.
Uses
1H-Indole-4-carboxylic acid, 1-[tris(1-methylethyl)silyl]-, ethyl ester is commonly used as a reagent in organic synthesis, particularly in the preparation of indole derivatives with various functional groups. It is also used as a building block in the synthesis of pharmaceuticals and bioactive compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 112447-71-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,4,4 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 112447-71:
(8*1)+(7*1)+(6*2)+(5*4)+(4*4)+(3*7)+(2*7)+(1*1)=99
99 % 10 = 9
So 112447-71-9 is a valid CAS Registry Number.
