112473-27-5Relevant articles and documents
Nucleophilic Substitution of Aromatic Halides with Amines under High Pressure
Ibata, Toshikazu,Isogami, Yasushi,Toyoda, Jiro
, p. 1187 - 1190 (1987)
The reaction of aromatic chlorides, bromides and iodides with various primary or secondary amines in a tetrahydrofuran solution under high pressure of 6-12 kbar gave the corresponding secondary and tertiary aromatic amines. 1,4-Diazabicyclooctane and quinuclidine gave N-aryl quaternary ammonium halides in high yields in contrast to the low reactivity of acyclic tertiary amines.