112482-40-3Relevant academic research and scientific papers
Regioselective Opening of Simple Epoxides with Diisopropylamine Trihydrofluoride
Muehlbacher, Manfred,Poulter, C. Dale
, p. 1026 - 1030 (2007/10/02)
Treatment of benzyl ether derivatives of simple aliphatic epoxy alcohols with diisopropylamine trihydrofluoride gave mixtures of the corresponding fluorohydrins in good yields.Steric hindrance is a major factor in determining the regioselectivity of epoxide opening, although electronic effects cannot be ignored.Electronic effects are more dominant with pyridine polyhydrofluoride.
