1125-28-6

Basic information

• Product Name: 1-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-ETHANONE
• Synonyms: ART-CHEM-BB B018671;CHEMBRDG-BB 4002435;1-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-ETHANONE;AKOS B018671;AKOS PAO-0389;VITAS-BB TBB006531;1-(1,3,5-trimethylpyrazol-4-yl)ethanone;1-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethanone(SALTDATA: FREE)
• CAS NO: 1125-28-6
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.19
• Mol File: 1125-28-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 243.4°C at 760 mmHg
• Flash Point: 101°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.0321mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-ETHANONE(1125-28-6)
• EPA Substance Registry System: 1-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-ETHANONE(1125-28-6)

Safety Data

• Hazardous Substances Data: 1125-28-6(Hazardous Substances Data)

Usage

General Description

1-(1,3,5-Trimethyl-1H-pyrazol-4-yl)-ethanone is a chemical compound with the molecular formula C9H14N2O. It is a derivative of pyrazole and contains a ketone functional group. 1-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-ETHANONE is commonly used in organic synthesis as a building block for the preparation of various other organic compounds. It may also have potential applications in the field of pharmaceuticals and agrochemicals due to its structural features. Overall, 1-(1,3,5-Trimethyl-1H-pyrazol-4-yl)-ethanone is a versatile and important chemical compound with various potential uses in different industries.

InChI:InChI=1/C8H12N2O/c1-5-8(7(3)11)6(2)10(4)9-5/h1-4H3

Upstream product

• 59487-13-7 N-tert-butyl-4-amino-3-penten-2-one 
• 60-34-4 methylhydrazine 
• 343866-85-3 3-acetyl-4-(t-butylamino)-3-penten-2-one 

Relevant articles and documents

Study of the reactivity of α-acylenaminoketones. Synthesis of pyrazoles

The reactions of 4-(methylamino)-3-penten-2-one with diazoketones yielded the α-acylenaminoketones 1-3 in good yields. Preparation of the α-acylenaminoketone 4 was carried out by treatment of 4-(t-butylamino)-3-penten-2-one with benzoyl chloride being followed by reaction of transamination with methylamine. The reactions were carried out in five different solvents and were submitted to gas chromatography/mass spectrometry analysis, with the goal of obtaining substituted pyrazoles and determining which of the carbonyls would preferentially be attacked by the nucleophile. The reactions of compounds 1-4 with hydrazine reagents led to the formation of the pyrazoles 5-7a-q. Small amounts of 4-methylamino-2-pentenones 10a-q, amides 11a-q and pyrazoles 12a-q were also obtained in these reactions. The unexpected formation of pyrazoles 15d,h,q was detected when methanol and N,N-dimethylformamide were used as solvents in the reactions of α-acylenaminoketone 4 with hydrazine reagents.