112513-79-8Relevant articles and documents
Heterocycles 10. A facile synthesis of 7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Weintraub,Tiernan,Huffman
, p. 561 - 563 (1987)
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SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE
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Page/Page column 135, (2020/12/11)
The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.
BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
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Page/Page column 60; 61, (2019/02/02)
The invention provides novel compounds having the general formula (I): (I) wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
Enantioselective Black rearrangement catalyzed by chiral bicyclic imidazole
Wang, Mingli,Zhang, Zhenfeng,Liu, Shan,Xie, Fang,Zhang, Wanbin
supporting information, p. 1227 - 1230 (2014/02/14)
A newly developed chiral imidazole nucleophilic catalyst, Acyloxy-DPI, was readily prepared and successfully applied to the enantioselective Black rearrangement with up to 88% ee for a wide range of substrates possessing different substituted groups. A pl