112533-07-0 Usage
Uses
Used in Pharmaceutical Industry:
1-((6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-3-en-3-ylmethyl)-1-methyl-pyrrolidinium; chloride is used as a potential pharmaceutical compound for its unique molecular structure and functional groups, which may contribute to the development of new drugs or drug candidates.
Used in Organic Synthesis:
In the field of organic synthesis, 1-((6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-3-en-3-ylmethyl)-1-methyl-pyrrolidinium; chloride can be used as a building block or intermediate for the synthesis of more complex molecules, taking advantage of its reactive functional groups and bicyclic ring system.
Used as a Research Reagent:
1-((6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-3-en-3-ylmethyl)-1-methyl-pyrrolidinium; chloride can also be utilized as a research reagent in academic and industrial laboratories. It may be employed to study various chemical reactions, mechanisms, and interactions with other molecules, providing valuable insights into its properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 112533-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,5,3 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 112533-07:
(8*1)+(7*1)+(6*2)+(5*5)+(4*3)+(3*3)+(2*0)+(1*7)=80
80 % 10 = 0
So 112533-07-0 is a valid CAS Registry Number.
112533-07-0Relevant articles and documents
Use of Bistrimethylsilylated Intermediates in the Preparation of Semisynthetic 7-Amino-3-substituted-cephems. Expedient Syntheses of a New 3-cephalosporin
Walker, Donald G.,Brodfuehrer, Paul R.,Brundidge, Steven P.,Shih, Kun Mao,Sapino, Chester
, p. 983 - 991 (2007/10/02)
Several "one-pot" methods for conversion of 7-ACA (6) to a variety of 7-amino-3-(ammoniomethyl)- or 7-amino-3-methyl>cephalosporin derivatives via bistrimethylsilylated intermediates are presented.For example, bistrimethylsilylation of 7-ACA (6) in 1,1,2-trichlorotrifluoroethane (Freon TF) using HMDS and 3 mol percent TMSI, followed by treatment with 1.15 equiv of TMSI and subsequent reactions with tertiary alicyclic or heteroaromatic amines or heteroaromatic thiols, led to the desired products in good yields.Alternatively, novel reaction of the bistrimethylsilylated derivative 15 with amine/TMSI adducts in Freon TF at 35 deg C provided an alternative approach to some 7-amino-3-(ammoniomethyl)cephalosporins.The solvent dependence of Δ3/Δ2 isomer ratios in quaternization reactions of 11 with N-methylpyrrolidine is presented.Hypotheses for the explanation of experimental results observed on reaction of 15 in Freon TF with amine/TMSI adducts are presented.Acylation of 17 (X = Cl, I) with 8 in aqueous THF provided 18 (BMY-28142) as its sulfate salt in overall yields of 18percent and 43percent, respectively, from 7-ACA (6).
