1125407-02-4

Basic information

• Product Name: C₁₈H₂₂BrN₃O₃
• Synonyms: C₁₈H₂₂BrN₃O₃
• CAS NO: 1125407-02-4
• Molecular Weight: 408.295
• Mol File: 1125407-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₂BrN₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₂BrN₃O₃(1125407-02-4)
• EPA Substance Registry System: C₁₈H₂₂BrN₃O₃(1125407-02-4)

Safety Data

• Hazardous Substances Data: 1125407-02-4(Hazardous Substances Data)

Upstream product

• 887913-52-2 (methylamino)thioxomethylcarbamic acid t-butyl ester 

Relevant articles and documents

ASPARTYL PROTEASE INHIBITORS

Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein j, k, U, W, R, R1, R2, R3, R4, R6, R7 and R7a are as described above in the specification. Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula (I) in combination with a cholinesterase inhibitor or a muscarinic m1 agonist or m2 antagonist.