1125465-75-9Relevant academic research and scientific papers
HIV INTEGRASE INHIBITORS
-
Page/Page column 81, (2012/08/27)
Provided herein, inter alia, are novel compounds for the inhibition of HIV integrase. The compounds disclosed herein are useful for methods of treating HIV infection in a subject in need thereof.
Thioamide hydroxypyrothiones supersede amide hydroxypyrothiones in potency against anthrax lethal factor
Agrawal, Arpita,De Oliveira, César Augusto F.,Cheng, Yuhui,Jacobsen, Jennifer A.,McCammon, J. Andrew,Cohen, Seth M.
experimental part, p. 1063 - 1074 (2009/12/08)
Anthrax lethal factor (LF) is a critical virulence factor in the pathogenesis of anthrax. A structure-activity relationship (SAR) of potential lethal factor inhibitors (LFi) is presented in which the zinc-binding group (ZBG), linker, and backbone moieties
