1125465-83-9Relevant academic research and scientific papers
Thioamide hydroxypyrothiones supersede amide hydroxypyrothiones in potency against anthrax lethal factor
Agrawal, Arpita,De Oliveira, César Augusto F.,Cheng, Yuhui,Jacobsen, Jennifer A.,McCammon, J. Andrew,Cohen, Seth M.
experimental part, p. 1063 - 1074 (2009/12/08)
Anthrax lethal factor (LF) is a critical virulence factor in the pathogenesis of anthrax. A structure-activity relationship (SAR) of potential lethal factor inhibitors (LFi) is presented in which the zinc-binding group (ZBG), linker, and backbone moieties
