1125595-64-3Relevant academic research and scientific papers
News from the 80-year-old passerini variant of the Friedel-Crafts alkylation of indole
Desimoni, Giovanni,Faita, Giuseppe,Mella, Mariella,Toscanini, Marco,Boiocchi, Massimo
experimental part, p. 6232 - 6238 (2009/06/18)
The multi-component Friedel-Crafts alkylation reaction between indole (1), ethyl glyoxylate (2) and anilines (3a-f) gives, in analogy to the protocol of the old Passerini reaction, the expected ethyl 2-(arylamino)-2-(1H-indol-3-yl) acetates 4a-f. When the
