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Dexecadotril, also known as Retorphan, is a potent and selective inhibitor of the enzyme neprilysin. It is derived from the enantiomers of Thiorphan (T369500) and is being developed as a therapeutic agent. Dexecadotril exhibits strong inhibitory effects on the target enzyme, making it a promising candidate for various medical applications.

112573-72-5

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112573-72-5 Usage

Uses

Used in Pharmaceutical Industry:
Dexecadotril is used as a therapeutic agent for the inhibition of neprilysin, an enzyme involved in the degradation of various peptides and proteins. Its selective inhibition can potentially lead to the development of novel treatments for a range of medical conditions.
Used in Neurodegenerative Disease Treatment:
Dexecadotril is used as a potential treatment for neurodegenerative diseases, such as Alzheimer's and Parkinson's, where the inhibition of neprilysin can help slow down the progression of the disease by reducing the degradation of certain neurotransmitters and bioactive peptides.
Used in Pain Management:
Dexecadotril is used as an analgesic agent, particularly for the management of chronic pain conditions. Its potent inhibition of neprilysin can lead to increased levels of endogenous pain-relieving substances, providing relief from chronic pain.
Used in Drug Development:
Dexecadotril serves as a prodrug for the enantiomers of Thiorphan (T369500), which can be further developed and optimized for specific medical applications. Its development can lead to the creation of more effective and targeted therapies for various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 112573-72-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,5,7 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 112573-72:
(8*1)+(7*1)+(6*2)+(5*5)+(4*7)+(3*3)+(2*7)+(1*2)=105
105 % 10 = 5
So 112573-72-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)/t19-/m0/s1

112573-72-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name benzyl 2-[[(2R)-2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate

1.2 Other means of identification

Product number -
Other names Dexecadotril

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112573-72-5 SDS

112573-72-5Upstream product

112573-72-5Downstream Products

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