112581-74-5 Usage
General Description
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidine is a chemical compound with a pyrazole-pyrimidine fused ring structure. It is a heterocyclic compound that is commonly used as a potent and selective antagonist for the adenosine A1 receptor. This chemical also acts as an agonist for the A2A adenosine receptor. It has been studied for its potential therapeutic applications in the treatment of various neurological disorders, including neurodegenerative diseases, Parkinson's disease, and Alzheimer's disease. Additionally, 2,5,7-Trimethylpyrazolo[1,5-a]pyrimidine has shown promise in the field of cancer research due to its ability to inhibit the growth and proliferation of cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 112581-74-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,5,8 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 112581-74:
(8*1)+(7*1)+(6*2)+(5*5)+(4*8)+(3*1)+(2*7)+(1*4)=105
105 % 10 = 5
So 112581-74-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H11N3/c1-6-4-8(3)12-9(10-6)5-7(2)11-12/h4-5H,1-3H3
112581-74-5Relevant articles and documents
Pyrazolopyrimidines based on 5-aminopyrazoles unsubstituted at the position 1
Nam,Grandberg,Sorokin
, p. 1371 - 1374 (2002)
By condensation of various symmetric β-diketones with a series of 5-aminopyrazoles that are unsubstituted at the position 1, we have obtained a series of pyrazolo[1,5-a]pyrimidines that are of interest as physiologically active compounds. Hexafluoroacetylacetone reacts in another direction, forming pyrazolo[4,5-b]pyridine.
Convenient synthesis of substituted 3-alkenylpyrazolo[1,5-a]pyrimidines via Heck cross-coupling reaction
Yin, Lunxiang,Liebscher, Juergen
, p. 2329 - 2334 (2007/10/03)
3-Iodopyrazolo[1,5-a]pyrimidines 3 were easily obtained by direct iodination of pyrazolo[1,5-a]pyrimidines 2 with NIS and could be transformed into a series of new substituted 3-alkenyl-pyrazolo[1,5-a]pyrimidines 5 by Heck cross-coupling.
