112604-11-2Relevant academic research and scientific papers
Fragment-based drug design targeting syntenin PDZ2 domain involved in exosomal release and tumour spread
Barral, Karine,Benmansour, Fatiha,Derviaux, Carine,Egea-Jimenez, Antonio Luis,Feracci, Mikael,Garcia, Manon,Hoffer, Laurent,Morelli, Xavier,Roche, Philippe,Zimmermann, Pascale,Leblanc, Rapha?l
, (2021)
Syntenin stimulates exosome production and its expression is upregulated in many cancers and implicated in the spread of metastatic tumor. These effects are supported by syntenin PDZ domains interacting with syndecans. We therefore aimed to develop, throu
HYDROXY-ETHYLENE DERIVATIVES FOR THE TREATMENT OF ARTHROSIS
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Paragraph 0247-0248, (2016/06/13)
The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering
