112607-23-5Relevant academic research and scientific papers
Preparation of optically active 4-substituted γ-lactones by lipase-catalyzed optical resolution
Shimotori, Yasutaka,Hoshi, Masayuki,Inoue, Keita,Osanai, Takeshi,Okabe, Hayato,Miyakoshi, Tetsuo
, p. 165 - 174 (2015/06/25)
Optically active 4-substituted γ-lactones (3 and 4) were synthesized effectively using lipase-catalyzed optical resolution. N-methyl-4-hydroxyalkanamides (rac-1a-i) as substrates were prepared from N-methylsuccinimide. The alkylation of N-methylsuccinimid
Enantio- and diastereocontrolled total synthesis of (+)-strictifolione
Kumar, Pradeep,Pandey, Menaka,Gupta, Priti,Naidu, S. Vasudeva,Dhavale, Dilip D.
scheme or table, p. 6993 - 7004 (2011/02/25)
A concise and practical enantioselective synthesis of (+)-strictifolione has been achieved in high diastereomeric excess using Jacobsen's hydrolytic kinetic resolution, proline-catalyzed sequential α-aminoxylation and Horner-Wadsworth-Emmons olefination o
Catalytic enantioselective synthesis of 2-alkylcyclobutanones and 4-alkyl-γ-butyrolactones from alkylidenecyclopropanes and the Sharpless AD-mix reagent
Krief, Alain,Ronvaux, Alain,Tuch, Arounarith
, p. 699 - 702 (2007/10/03)
Reaction of AD-mix with alkylidenecyclopropanes allows the synthesis of optically active 2-alkylcyclobutanones and 4-alkyl-γ-butyrolactones after stepwise pinacolic rearrangement and Beyer-Villiger oxidation.
Baker's yeast reduction of arylalkyl and arylalkenil γ- and δ-keto acids
Aquino, Mario,Cardani, Silvia,Fronza, Giovanni,Fuganti, Claudio,Fernandez, Rosalino Pulido,Tagliani, Auro
, p. 7887 - 7896 (2007/10/02)
γ- and δ-Lactones 5, 6, 13, 14, 15 and 16 were synthesized via baker's yeast reduction of the corresponding keto acids 3, 4 and 9-12. The enantioselectivity of the reduction is strongly dependent on the nature of the keto acid; the δ-lactones ware always obtained in an ee% higher than the γ-lactones and ranging from 70% to 100%.
